UC Davis team wins $3.3 million grant to conduct juvenile

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A husband-and-wife research team at the UC Davis School of Medicine has been awarded a five-year, $3.3 million grant to lead a nationwide study on how to prevent brain swelling in children with diabetes.

A "diabetic crisis" occurs when the body releases acidic ketones into the blood, a byproduct of burning fat stores for energy. They can result in neurological injuries and sometimes death.

The award's recipients are Nathan Kuppermann, professor of emergency medicine and pediatrics and chair of the Department of Emergency Medicine, and Nicole Glaser, associate professor of pediatric endocrinology. The Eunice Kennedy Shriver National Institute of Child Health and Human Development is funding the grant.
Call The Bee's Anna Tong, (916) 321-1045.

The two UC Davis doctors plan to enroll 1,500 children in the study, which will examine the best way to rehydrate children in diabetic crisis in hospital emergency departments, in order to minimize adverse neurological outcomes. They will begin enrolling children in the fall.